Catalog Number: 20767174160
For cobas c 311/501 analyzers:
In vitro test for the quantitative determination of toxic levels of acetaminophen in serum and plasma on Roche/Hitachi cobas c systems.
|Shelf life at 2 to 8° C:Do not freeze.||See expiration date on cobas c pack label|
|On-board in use and refrigerated on the analyzer:||21 weeks|
Specimen collection and preparation
Deselect Automatic Rerun for these applications in the Utility menu, Application screen, Range tab.
Traceability: This method has been standardized against USP reference materials. The calibrators are prepared to contain known quantities of acetaminophen in buffer.
|Calibrators||S1-2: COBAS Acetaminophen Calibrators|
|Calibration frequency||2 point calibration- after cobas c pack change- as required following quality control procedures|
15.0-500 µg/mL (99.3-3310 µmol/L)
Limit of Blank (LoB), Limit of Detection (LoD) and Limit of Quantitation (LoQ)
Representative performance data on the analyzers are given below. Results obtained in individual laboratories may differ.
Precision was determined using human samples and controls in a modified NCCLS EP5-T2 protocol (repeatability n = 63, intermediate precision n = 63). The following results were obtained on a Roche/Hitachi cobas c 501 analyzer.
Acetaminophen values for human serum and plasma samples obtained on Roche/Hitachi cobas c 501 analyzer (y) were compared to those determined with the same reagent on COBAS INTEGRA 800 analyzer (x) and Roche/Hitachi 917 analyzer (x).
The following compounds were tested for cross-reactivity.