Technical specs

The cobas® 6000 analyzer series provides customizable solutions for efficient, top-quality mid-volume testing.



Drive lab efficiency with standard instrumentation, reference ranges, consumables, and usage.

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Minimize downtime with industry-leading engineering and service.

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Easily manage peak testing volume and scale efficiently with the modular analyzer design.

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Rapid TAT

Speed up turnaround time for high-volume and STAT assays, for a new level of fast service.

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7 different series configurations

Flexible modularity offers individualized solutions to easily meet your challenging workflow needs. System design allows for easy system reconfiguration on-site to meet the changing needs and growth of your laboratory into the future.


Core Unit

Simple operation with continuous loading and unloading

Loading capacity of 150 samples in two trays of 75

Load 5-position racks via dedicated STAT port with rerun buffer or by tray

Unique 5-position rack for more efficient sample handling

Smart track rotor for intelligent sample handling

Single control unit for all modules

Take a deeper look at the cobas 6000 system


cobas 6000 explore: Application showcase


cobas 6000 3d build: Application showcase


cobas c 501 module

Clinical chemistry, homogeneous immunoassays, ISE, HbA1c (whole blood measurement).


Throughput of up to 1,000 tests/hour

60 reagent channels plus 3 ISE's

Reagent loading on the fly

Specimen integrity via serum indices (parallel processing), clot and liquid level detection

Contact-free ultrasonic mixing

Automated rerun and dilution



cobas e 601 module

Heterogeneous immunoassays including cardiac markers, anemia, bone and tumor markers, hormones, and infectious diseases.


Electrochemiluminscence (ECL) technology

Throughput up to 170 tests/hour

25 reagent channels

Carry-over free disposable tips and cups

9-minute STAT applications for Troponin I and T, proBNP II, Myoglobin, hCG and CKMB

Clot and liquid level detection

Automated rerun and dilution


Technical Specifications

System 2nd Generation SWA: modular, analytical system platform, consolidated work area for Clinical Chemistry and Immunology, expandable and re-configurable on site 
Types of Modules
cobas c 501 module Photometric measuring unit (incl. ISE) 
cobas e 601 module Electrochemiluminescence (ECL) technology measuring unit 
Number of module combinations

7 module combinations, Up to 3 modules in one core unit

cobas c 501 modules 1 to 2 modules
cobas e 601 modules 1 to 2 modules
cobas c 501 | cobas e 601 modules 2 to 3 modules (only 2 unites of 1 module type for SWA combinations possbile)
Sample throughput Up to 120 racks/hr or 600 samples/hr

Test throughput

(theoretical max)

170 up to 2,170 tests/hr overall
1,000 up to 2,000 tests/hr with cobas c 501 modules
170 up to 340 tests/hr with cobas e 601 modules
1,170 up to 2,170 tests/hr with cobas c 501 and cobas e 601 modules

Number of channels

(reagent slots)

Up to 151 channels, in total

63 channels (including ISE, automatic setting) on cobas c 501 module

25 channels on cobas e 601 module

Sample material Serum, Plasma, Urine, CSF
Core unit analytics
Rack 5 position rack, RD standard rack
Rack types Routine, STAT, Control, Calibrator, Rerun (manual), Wash
Tray Tray with 15 racks/75 samples, RD standard tray
STAT port STAT samples are processed with true STAT interrupt
Sample container types
Primary tubes 5 to 10 mL; 16 x 100, 16 x 75, 13 x 100, 13 x 75 mm
Sample cup 2.5 mL
Micro cup 1.5 mL, (exception: cobas e 601 module)
Cups on tube Cup on top of a 16 x 75/100 mm tube; Cup on top of one non standard tube
False bottom tube (FBT) One type is definable
Sample volume 1 - 35 µL
Sample dilution 3 - 121 times
Sample clot detection Available for cobas c 501 and cobas e 601 module
Minimum sample volume
Primary tubes 700 µL
Sample cup 100 µL
Micro cup (FTB) 50 µL
Sample barcode types

Code 128; Codabar (NW 7); Interleaved 2 of 5; Code 39

System interfaces

RS 232 serial interface, bi-directional

Interface to cobas link data station for cobas teleservice functionalities and automatic download

Sample data base 10.000 routine/STAT samples
Test methods For photometric modules: 1 point, 1 point + prozone check, 2 point, 2 point kinetic, 2 point + prozone check, 3 point, 1 point + kinetics Rate A, Rate A + serum index, Rate A with blank, Rate B
Calibrator/QC input Via specified racks through the input buffer or STAT port
Calibration methods

Start-up, Re-calibration

For photometric modules: Linear, non-linear multi-points, 2 point calibration, K-factor up to 100 different calibrators pre-programmable

Storage of up to 180 curves

Preventive calibration of the stand-by cobas c and cobas e packs on cobas c 501: Two k-factor can be defined for different sample types

QC methods

For e- and photometric modules: Real-time QC, individual QC, cumulative QC

Up to 100 controls pre-programmable

Preventive QC after calibration of the stand-by cassettes/rack packs

Auto QC: QC without operator intervention (timer triggered)

Rerun/reflex function 

Automatic rerun and manual rerun


Automatic reflex is supported by the system, reflex request to be provided by Roche Middleware Solutions

Electrical requirements
Power requirements 230 Volts AC; 110 Volts AC 2.4 kVA (for cobas c 501 | e 601)
Frequency 50 Hz or 60 Hz +/- 0.5 %
Water/waste requirements

Bacteria free, deionised water supply: resistance of < 1,0 µS/cm

Water pressure 0.5 – 3.5 kg/cm3, (49 - 343 Kpa)
Biohazards waste Separate container behind the system
L. concentrated Central drain port, diameter: = 50 mm / 2 inches
Waste drain < waste 100 mm above the floor / 4 inches
Water consumption
Max flow rate cobas c 501 module: approx. 40 L/hr
Typical consumption cobas e 601 module: approx. 30 L/hr
Operating conditions
Ambient temperature 15 to 32 °C / 59 to 90 °F
Ambient humidity 30 to 85 % (RH, without condensation)
Heat output 1.5 kW (5400 kJ/hr for cobas c 501, 4320 kJ/hr for cobas e 601)
Noise output < 65 dB
Physical dimensions
Width 188 to 498 cm / 74 to 196 inches
Core unit

69 cm / 27.2 inches

cobas c or cobas e module: 120 cm / 47.2 inches


cobas c or cobas e module: 98 cm / 38.6 inches

Core unit: 104 cm / 41 inches

Height 130 cm / 51 inches
Control unit Width: 80 cm / 31.5 inches, depth: 80 cm / 31.5 inches
cobas c 501 module 330 kg / 730 lb
cobas e 601 module 360 kg / 795 lb
Core unit (sample loader, control unit, rack rotor) 180 kg / 400 lb
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