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Overview

The cobas® 8000 modular analyzer series, with its flexible modularity, brings a new dimension of productivity, efficiency and consolidation.


Game-changing
testing efficiency
  • Eliminate bottlenecks during peak testing periods
  • Consolidate more testing on one scalable platform
  • Reduce waste with industry-leading reagent and calibration stability
Clinical insight when
minutes matter
  • Access Roche’s complete menu of high-value immunoassays, featuring PCT, AMH, NT-proBNP and Troponin T Gen 5
  • Treat critical patients sooner with 9-minute STAT assays
  • Reduce patient redraws with smaller sample volumes
A standardized platform
designed for growth
  • Enable population health management with standardized reference ranges
  • Minimize training costs and enable staff sharing with a common user interface
Accelerate testing efficiency and reduce errors with Roche automation and middleware
  • Bidirectional connectivity to cobas® 8100 automated workflow series
  • Interface with Roche middleware featuring Lab Intelligence
Explore

cobas® 8000 Data Manager

cobas 8000 data manager
  • Screen sharing with the analyzer software
  • Traceability of information for easy tracking of calibration and reagent information
  • User-defined fully automated and selective rerun and reflex testing
  • Technical validation of sample results in combination with rule programming improves and accelerates the result release process
  • QC management of all connnected instruments on a single screen supports flexible integration of local requirements for QC standards and rules (e.g., Levey-Jennnings plots and diagrams, Westgard rules, etc.)

Take a deeper look at the cobas 8000 system

cobas-8000-explore.png

cobas 8000 explore: Application showcase

cobas® 8000 Core Unit

  • Loading capacity of up to 300 samples (4 trays: 15 racks/tray, 5 samples/rack)
  • Throughput of up to 1,000 samples/hour
  • Dedicated STAT port
cobas 8000 core unit

cobas® 8000 ISE Module

cobas 8000 ISE module
  • Sodium, potassium, chloride
  • Up to 600 samples/hour or 1,800 tests/hour
  • ISE specific sample probe with clot detection
  • Indepedent processing line

Module Sample Buffer

  • Capacity for 20 sample racks/up to 100 samples per module
  • Environmentally controlled compartment for 5 Auto QC racks
  • Backup operation port
  • Rack shuttle gates allow fast and efficient movement of racks from module to module
  • True random access allows all racks to go from anywhere to everywhere
  • Seamless STAT integration
Module Sample Buffer

cobas® c 702 Module

cobas 702 Module
  • Clinical chemistry, homogeneous immunoassays
  • Throughput of up to 2,000 tests/hour
  • 70 reagent channels
  • Reagent loading on the fly
  • Specimen integrity via serum indices (parallel processing), clot and liquid level detection
  • Contact-free ultrasonic mixing
  • Reagent RFID reader
  • 2 sample probes 4 reagent probes
  • Effective cycle time of 1.8 seconds

cobas® c 502 Module

  • Clinical chemistry, homogeneous immunoassays, HbA1c (whole blood measurement)
  • Throughput of up to 600 tests/hour
  • 60 reagent channels
  • Reagent loading on the fly
  • Specimen integrity via serum indices (parallel processing), clot and liquid level detection
  • Contact-free ultrasonic mixing
cobas 502 Module

cobas® e 801 Module

cobas 801 Module
  • High-volume immunoassay testing
  • Electrochemiluminescence technology (ECL)
  • Up to 300 tests/hour
  • 48 reagent channels
  • No reagent preparation
  • 25% less sample volume than cobas e 602 module
  • Reagent Manager provides on-the-fly loading of up to 5 reagent cassettes during routine operation

cobas® e 602 Module

  • Heterogeneous immunoassays
  • Electrochemiluminescence (ECL) technology
  • Throughout of up to 170 tests/hour
  • 25 reagent channels
  • Disposable tips and cups
  • Clot and air bubble detection
cobas 602 Module
Performance

cobas® 8000 Technical Specifications

Configurations The system offers more than 150 scalable configurations. A configuration consists from the core unit and 1 up to 4 analytical modules (excluding the optional cobas ISE module).

The analytical modules are: cobas ISE module, cobas c 701 module, cobas c 702 module, cobas c 502 module, cobas e 801 module, cobas e 602 module.
Detection methods Clinical Chemistry: Photometric
Immunochemistry: Electrochemiluminescence (ECL)
Maximum throughput Up to 9800 tests/hour/configuration
  • cobas ISE module: up to 1800 tests/hour
  • cobas c 701 module: up to 2000 tests/hour
  • cobas c 702 module: up to 2000 tests/hour
  • cobas c 502 module: up to 600 tests/hour
  • cobas e 801 module: up to 300 tests/hour
  • cobas e 602 module: up to 170 tests/hour
Sample types Serum, Plasma, Urine, CSF, Supernatant, Whole blood (not applicable for the cobas c 701 module and the cobas c 702 module)
Sample tubes 13 x 75 mm, 13 x 100 mm, 16 x 75 mm, 16 x 100 mm, Hitachi standard cup 2.5 ml, cobas sample cup 2.5 ml, Hitachi microcup* 1.5 ml 11-16 x 63-102 mm (for cobas e 602 module: 13-16 mm)
Pediatric sample tube Yes (Hitachi microcup*: 50 µl dead volume)
Sample capacity Core unit loading capacity: 300 samples
Module Sample Buffer (MSB) capactiy: 100 samples
Core unit throughput: up to 1000 samples/hour
Sample volume
  • cobas c 701 module: Average 5.5 µl
  • cobas c 702 module: Average 5.5 µl
  • cobas c 502 module: Average 7.0 µl
  • cobas e 801 module: Average 19.4 µ
  • cobas e 602 module: Average 26.8 µl
Automatic dilution Yes
Reagent capacity Up to 280 reagent channels/configuration
  • cobas ISE module: Na, K and Cl
  • cobas c 701 module: 70 reagent channels
  • cobas c 702 module: 70 reagent channels
  • cobas c 502 module: 60 reagent channels
  • cobas e 801 module: 48 reagent channels
  • cobas e 602 module: 25 reagent channels
Reagent concept Ready to use
Reagent loading Continuous reagent loading during operation (valid for cobas c 702 module, cobas c 502 module and cobas e 801 module)
Sample clot detection Yes
Sample interference measurement Serum indices (icterus, hemolysis, lipemia) measured on the clinical chemistry modules
Remote diagnostics Yes
Connectivity to smart phones and tablets Up to 3 systems can be connected to smart phones and tablets (iOS and Android) using cobas mobicheck application. The application allows the monitoring of the systems, alarms and reagent information.
Dimensions (W x D x H)
  • Core unit (including STAT port): 102 x 114 x 93 cm
  • cobas ISE module: 45 x 114 x 115 cm
  • cobas c 701 module (including MSB): 150 x 114 x 135 cm
  • cobas c 702 module (including MSB): 150 x 114 x 135 cm
  • cobas c 502 module (including MSB): 150 x 114 x 130 cm
  • cobas e 801 module (including MSB): 150 x 114 x 162 cm
  • cobas e 602 module (including MSB): 150 x 106 x 114 cm
Weight
  • Core Unit: 197 kg
  • cobas ISE module: 180 kg (ISE 1800), 170 kg (ISE 900)
  • cobas c 701 module (including MSB): 697 kg
  • cobas c 702 module (including MSB): 759 kg
  • cobas c 502 module (including MSB): 535 kg
  • cobas e 801 module (including MSB): 610 kg
  • cobas e 602 module (including MSB): 585 kg
Electrical requirements 200/208/220/230 VAC, 50/60 Hz
Noise level ≤ 65 dB
Pre-Analytics connectivity Unidirectional, bidirectional
Power consumption
  • Core Unit (including the control unit): 1 kVA (actual maximum: 0.4 kVA)
  • cobas ISE module: 0.5 kVA (actual maximum: 0.2 kVA)
  • cobas c 701 module (including MSB): 3 kVA (actual maximum: 2.3 kVA)
  • cobas c 702 module (including MSB): 3 kVA (actual maximum: 2.3 kVA)
  • cobas c 502 module (including MSB): 2.5 kVA (actual maximum: 1.7 kVA)
  • cobas e 801 module (including MSB): 2 kVA (actual maximum: 1.5 kVA)
  • cobas e 602 module (including MSB): 3 kVA (actual maximum: 1.5 kVA)
Heat generation
  • Core Unit (including the control unit): 3600 kJ/h (actual maximum: 1440 kJ/h)
  • cobas ISE module: 1800 kJ/h (actual maximum: 720 kJ/h)
  • cobas c 701 module (including MSB): 10800 kJ/h (actual maximum: 8280 kJ/h)
  • cobas c 702 module (including MSB): 10800 kJ/h (actual maximum: 8280 kJ/h)
  • cobas c 502 module (including MSB): 9000 kJ/h (actual maximum: 6120 kJ/h)
  • cobas e 801 module (including MSB): 7200 kJ/h (actual maximum: 5400 kJ/h)
  • cobas e 602 module (including MSB): 10800 kJ/h (actual maximum: 5400 kJ/h)
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Strategic Resource Center Decision Guide

c 701

Anemia

Iron Gen.2
Tina-quant Ferritin Gen.4
Tina-quant Soluble Transferrin Receptor
Tina-quant Transferrin ver.2
Unsaturated Iron-Binding Capacity

Cardiac/Cardiac Markers

Cardiac C-Reactive Protein (Latex) High Sensitive
Cholesterol Gen.2
HDL-Cholesterol plus 3rd generation
LDL-Cholesterol Gen.3
Tina-quant Apolipoprotein A-1 ver.2
Tina-quant Apolipoprotein B ver.2
Tina-quant Lipoprotein (a) Gen.2
Tina-quant Myoglobin Gen.2
Triglycerides
Triglycerides/Glycerol Blanked

DAT

Ethanol Gen.2

Diabetes

Fructosamine
Glucose HK Gen.3
Tina-quant Albumin Gen.2

General Chemistry

Alanine Aminotransferase acc. to IFCC with pyridoxal phosphate activation
Alanine Aminotransferase acc. to IFCC without pyridoxal phosphate activation
Albumin BCP
Albumin Gen.2
Alkaline Phosphatase acc. to IFCC Gen.2
Ammonia
Aspartate Aminotransferase acc. to IFCC with pyridoxal phosphate activation
Aspartate Aminotransferase acc. to IFCC without pyridoxal phosphate activation
Bicarbonate Liquid
Bilirubin Total Gen.3
Calcium Gen.2
Creatine Kinase
Creatinine Jaffé Gen.2
Creatinine plus ver.2
Direct Bilirubin
Lactate Dehydrogenase acc. to IFCC ver.2
Lactate Gen. 2
Lipase colorimetric
Magnesium Gen.2
Phosphate (Inorganic) ver.2
Total Protein Gen.2
Total Protein Urine/CSF Gen.3
Urea/BUN
Uric Acid ver.2
g-Glutamyltransferase ver.2
α-Amylase EPS Pancreatic
α-Amylase EPS ver.2

STAT

Tina-quant Myoglobin Gen.2

Specific Proteins

C-Reactive Protein Gen.3
Cardiac C-Reactive Protein (Latex) High Sensitive
Ceruloplasmin
Homocysteine Enzymatic Assay
Prealbumin
Rheumatoid Factors
Tina-quant Antistreptolysin O
Tina-quant Complement C3c ver.2
Tina-quant Complement C4 ver.2
Tina-quant Cystatin C Gen.2
Tina-quant Haptoglobin ver.2
Tina-quant IgA Gen.2
Tina-quant IgG Gen.2
Tina-quant IgM Gen.2
Tina-quant α1-Acid Glycoprotein Gen.2
Tina-quant α1-Antitrypsin ver.2
Tina-quant β2-Microglobulin

Thyroid Function

CEDIA T Uptake
CEDIA T4

c 702

Anemia

Iron Gen.2
Tina-quant Ferritin Gen.4
Tina-quant Soluble Transferrin Receptor
Tina-quant Transferrin ver.2
Unsaturated Iron-Binding Capacity

Cardiac/Cardiac Markers

Cardiac C-Reactive Protein (Latex) High Sensitive
Cholesterol Gen.2
HDL-Cholesterol plus 3rd generation
LDL-Cholesterol Gen.3
Tina-quant Apolipoprotein A-1 ver.2
Tina-quant Apolipoprotein B ver.2
Tina-quant Lipoprotein (a) Gen.2
Tina-quant Myoglobin Gen.2
Triglycerides
Triglycerides/Glycerol Blanked

DAT

Ethanol Gen.2

Diabetes

Fructosamine
Glucose HK Gen.3
Tina-quant Albumin Gen.2

General Chemistry

Alanine Aminotransferase acc. to IFCC with pyridoxal phosphate activation
Alanine Aminotransferase acc. to IFCC without pyridoxal phosphate activation
Albumin BCP
Albumin Gen.2
Alkaline Phosphatase acc. to IFCC Gen.2
Ammonia
Aspartate Aminotransferase acc. to IFCC with pyridoxal phosphate activation
Aspartate Aminotransferase acc. to IFCC without pyridoxal phosphate activation
Bicarbonate Liquid
Bilirubin Total Gen.3
Calcium Gen.2
Creatine Kinase
Creatinine Jaffé Gen.2
Creatinine plus ver.2
Direct Bilirubin
Lactate Dehydrogenase acc. to IFCC ver.2
Lactate Gen. 2
Lipase colorimetric
Magnesium Gen.2
Phosphate (Inorganic) ver.2
Total Protein Gen.2
Total Protein Urine/CSF Gen.3
Urea/BUN
Uric Acid ver.2
g-Glutamyltransferase ver.2
α-Amylase EPS Pancreatic
α-Amylase EPS ver.2

STAT

Tina-quant Myoglobin Gen.2

Specific Proteins

C-Reactive Protein Gen.3
Cardiac C-Reactive Protein (Latex) High Sensitive
Ceruloplasmin
Homocysteine Enzymatic Assay
Prealbumin
Rheumatoid Factors
Tina-quant Antistreptolysin O
Tina-quant Complement C3c ver.2
Tina-quant Complement C4 ver.2
Tina-quant Cystatin C Gen.2
Tina-quant Haptoglobin ver.2
Tina-quant IgA Gen.2
Tina-quant IgG Gen.2
Tina-quant IgM Gen.2
Tina-quant α1-Acid Glycoprotein Gen.2
Tina-quant α1-Antitrypsin ver.2
Tina-quant β2-Microglobulin

Thyroid Function

CEDIA T Uptake
CEDIA T4

cobas c 502

Anemia

Iron Binding Capacity - Unsaturated
Iron Gen.2
Tina-quant Ferritin Gen.4
Tina-quant Soluble Transferrin Receptor
Tina-quant Transferrin ver.2

Cardiac/Cardiac Markers

Cardiac C-Reactive Protein (Latex) High Sensitive
Cholesterol Gen.2
Creatine Kinase-MB
Digoxin
HDL-Cholesterol Gen.4
HDL-Cholesterol plus 3rd generation
LDL-Cholesterol Gen.3
LDL-Cholesterol plus 2nd generation
Tina-quant Apolipoprotein A-1 ver.2
Tina-quant Apolipoprotein B ver.2
Tina-quant D-Dimer
Tina-quant Lipoprotein (a) Gen.2
Tina-quant Myoglobin Gen.2
Triglycerides
Triglycerides/Glycerol Blanked

Coagulation

Tina-quant D-Dimer

DAT

Amphetamines II
Barbiturates Plus
Benzodiazepines Plus
Cannabinoids II
Cocaine II
Ethanol Gen.2
Lysergic Acid Diethylamide
Methadone II
Opiates II
Oxycodone
Phencyclidine Plus
Propoxyphene Plus

Diabetes

Fructosamine
Glucose HK
HBA1C
Tina-quant Albumin Gen.2
Tina-quant Hemoglobin A1c Gen.2
Tina-quant Hemoglobin A1c Gen.3 - Hemolysate and Whole Blood Application

General Chemistry

Alanine Aminotransferase acc. to IFCC with pyridoxal phosphate activation
Alanine Aminotransferase acc. to IFCC without pyridoxal phosphate activation
Albumin BCP
Albumin Gen.2
Alkaline Phosphatase
Ammonia
Aspartate Aminotransferase acc. to IFCC with pyridoxal phosphate activation
Aspartate Aminotransferase acc. to IFCC without pyridoxal phosphate activation
Bicarbonate Liquid
Bilirubin Total Gen.3
Bilirubin direct
Calcium Gen.2
Cholinesterase
Cholinesterase Gen.2
Creatine Kinase
Creatine Kinase
Creatine Kinase-MB
Creatinine Jaffé Gen.2
Creatinine plus ver.2
Direct Bilirubin
Lactate Dehydrogenase acc. to IFCC ver.2
Lactate Gen.2
Lipase colorimetric assay
Magnesium
Magnesium Gen.2
Phosphate (Inorganic) ver.2
Total Protein Gen. 2
Total Protein Urine/CSF Gen.3
Urea/BUN
Uric Acid ver.2
a-Amylase EPS Pancreatic
a-Amylase EPS ver.2
g-Glutamyltransferase ver.2

STAT

Creatine Kinase-MB
Tina-quant Myoglobin Gen.2

Specific Proteins

C-Reactive Protein
C-Reactive Protein Gen.3
Cardiac C-Reactive Protein (Latex) High Sensitive
Ceruloplasmin
Homocysteine Enzymatic Assay
Prealbumin
Rheumatoid Factors II
Tina-quant Antistreptolysin O
Tina-quant Complement C3c ver.2
Tina-quant Complement C4 ver.2
Tina-quant Cystatin C Gen.2
Tina-quant Haptoglobin ver.2
Tina-quant IgA Gen.2
Tina-quant IgG Gen.2
Tina-quant IgM Gen.2
Tina-quant a1-Acid Glycoprotein Gen.2
Tina-quant a1–Antitrypsin ver.2
Tina-quant β2-Microglobulin

Specimen Validity

ONLINE DAT Specimen Validity Test Chromate
ONLINE DAT Specimen Validity Test Creatinine
ONLINE DAT Specimen Validity Test Nitrite
ONLINE DAT Specimen Validity Test Oxidant
ONLINE DAT Specimen Validity Test Specific Gravity
ONLINE DAT Specimen Validity Test pH

TDM

Acetaminophen
Acetaminophen
Amikacin
Carbamazepine
Digoxin
Gentamicin
Lithium
Mycophenolic Acid
N-acetylprocainamide
ONLINE TDM Acetaminophen Gen.2
ONLINE TDM Carbamazepine Gen.4
ONLINE TDM Vancomycin Gen.3
Phenobarbital
Phenytoin
Procainamide
Quinidine
Salicylate
Theophylline
Tobramycin
Valproic Acid
Vancomycin

cobas e 602

Anemia

Ferritin
Ferritin
Folate
Folate III
Folate RBC
Folate RBC Hemolyzing Reagent
Vitamin B12
Vitamin B12 II

Bone Markers

25-Hydroxyvitamin D
Osteocalcin (OCN)
Parathyroid hormone (parathormone, parathyrin) - PTH, intact
Parathyroid hormone (parathormone, parathyrin) - PTH, intact (STAT "Short Turn Around Time")
β-CrossLaps/serum (β-CTx in serum)

Cardiac/Cardiac Markers

CK-MB - the MB isoenzyme of creatine kinase
CK-MB - the MB isoenzyme of creatine kinase (STAT "Short Turn Around Time")
Digoxin
Elecsys Troponin T Gen 5 STAT
Myoglobin
Myoglobin STAT (Short Turn Around Time)
N-terminal pro B-type natriuretic peptide, STAT
Troponin I
Troponin I STAT (Short Turn Around Time)
Troponin T STAT (Short Turn Around Time), CARDIAC T
Troponin T, CARDIAC T
proBNP II

Diabetes

Connecting peptide
Insulin

Fertility/Hormones

ACTH
Cortisol
Cortisol
Dehydroepiandrosterone sulfate
Estradiol III
Follicle-stimulating hormone
Human sex hormone-binding globulin
Intact human chorionic gonadotropin + the β-subunit
Luteinizing hormone
Progesterone
Progesterone
Prolactin II
Testosterone

General Chemistry

CK-MB - the MB isoenzyme of creatine kinase
CK-MB - the MB isoenzyme of creatine kinase (STAT "Short Turn Around Time")

Growth Hormones

Human growth hormone

Hepatitis

Anti HCV
Antibodies to hepatitis B core antigen (anti-HBc)
Antibody to hepatitis B surface antigen (anti-HBs)
Antibody to hepatitis C virus (anti-HCV)
HBsAg Confirmatory Test
HBsAg Confirmatory Test
Hepatitis B surface antigen
Hepatitis B surface antigen
IgM antibodies to hepatitis B core antigen (anti-HBc IgM)
IgM antibodies to the hepatitis A virus
Total antibodies (IgM and IgG) to the hepatitis A virus

Infectious Disease

CMV IgG
Cytomegalovirus IgM
HSV-2 IgG
IgG antibodies to Cytomegalovirus
IgG antibodies to Rubella virus
IgG antibodies to Toxoplasma gondii
IgG antibodies to herpes simplex virus type 1
IgM antibodies to Cytomegalovirus
IgM antibodies to Rubella virus

Rheumatoid Arthritis

Antibody to cyclic citrullinated peptide (anti-CCP)

STAT

CK-MB - the MB isoenzyme of creatine kinase
CK-MB - the MB isoenzyme of creatine kinase (STAT "Short Turn Around Time")
Elecsys Troponin T Gen 5 STAT
Human chorionic gonadotropin (Short Turn Around Time)
Myoglobin
Myoglobin STAT (Short Turn Around Time)
N-terminal pro B-type natriuretic peptide, STAT
Parathyroid hormone (parathormone, parathyrin) - PTH, intact
Parathyroid hormone (parathormone, parathyrin) - PTH, intact (STAT "Short Turn Around Time")
Troponin I
Troponin I STAT (Short Turn Around Time)
Troponin T STAT (Short Turn Around Time), CARDIAC T
Troponin T, CARDIAC T
proBNP II

Sepsis

Procalcitonin

Specific Proteins

Immunoglobulin E

TDM

Digoxin

Thyroid Function

Antibodies to TSH receptor
Antibodies to thyroid peroxidase
Antibody to thyroglobulin (anti-Tg)
Free Triiodothyronine
Free thyroxine
T-Uptake
Thyrotropin
Thyroxine
Triiodothyronine
hCT - human calcitonin

Tumor Markers

AFP α1-fetoprotein
AFP α1-fetoprotein
Cancer Antigen 125
Cancer Antigen 15-3 II
Carbohydrate Antigen 19-9
Carcinoembryonic antigen
Carcinoembryonic antigen
Elecsys CYFRA 21-1
Free PSA
Human epididymal protein 4
total (free + complexed) PSA - Prostate-specific antigen (tPSA)
total (free + complexed) PSA - Prostate-specific antigen (tPSA)

Women's Health

Syphilis

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