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7 different series configurations

Flexible modularity offers individualized solutions to easily meet your challenging workflow needs. System design allows for easy system reconfiguration on-site to meet the changing needs and growth of your laboratory into the future.

cobas 6000 core unit

Core Unit

  • Simple operation with continuous loading and unloading
  • Loading capacity of 150 samples in two trays of 75
  • Load 5-position racks via dedicated STAT port with rerun buffer or by tray
  • Unique 5-position rack for more efficient sample handling
  • Smart track rotor for intelligent sample handling
  • Single control unit for all modules

Take a deeper look at the cobas 6000 system


cobas 6000 explore: Application showcase


cobas 6000 3d build: Application showcase


cobas® c 501 module

Clinical chemistry, homogeneous immunoassays, ISE, HbA1c (whole blood measurement).

  • Throughput of up to 1,000 tests/hour
  • 60 reagent channels plus 3 ISE's
  • Reagent loading on the fly
  • Specimen integrity via serum indices (parallel processing), clot and liquid level detection
  • Contact-free ultrasonic mixing
  • Automated rerun and dilution
cobas c 501 module

cobas® e 601 module

Heterogeneous immunoassays including cardiac markers, anemia, bone and tumor markers, hormones, and infectious diseases.

cobas e 601 module
  • Electrochemiluminscence (ECL) technology
  • Throughput up to 170 tests/hour
  • 25 reagent channels
  • Carry-over free disposable tips and cups
  • 9-minute STAT applications for Troponin I and T, proBNP II, Myoglobin, hCG and CKMB
  • Clot and liquid level detection
  • Automated rerun and dilution

cobas® 6000 Technical Specifications

System 2nd Generation SWA: modular, analytical system platform, consolidated work area for Clinical Chemistry and Immunology, expandable and re-configurable on site
Types of modules
  • cobas c 501 module: Photometric measuring unit (incl. ISE)
  • cobas e 601 module: Electrochemiluminescence (ECL) technology measuring unit
Number of configurations 7 module combinations; Up to 3 modules in one core unit
  • cobas c 501 modules: 1 to 2 modules
  • cobas e 601 modules: 1 to 2 modules
  • cobas c 501 | cobas e 601 modules: 2 to 3 modules (only 2 units of 1 module type for SWA combinations possbile)
Sample throughput Up to 120 racks/hour or 600 samples/hour
Test throughput
(theoretical max)
  • 170 up to 2,170 tests/hour: overall
  • 1,000 up to 2,000 tests/hour:with cobas c 501 modules
  • 170 up to 340 tests/hour:with cobas e 601 modules
  • 1,170 up to 2,170 tests/hour: with cobas c 501 and cobas e 601 modules
Number of reagent channels
(reagent slots)
Up to 151 channels, in total 63 channels (including ISE, automatic setting) on cobas c 501 module 25 channels on cobas e 601 module
Sample material Serum, Plasma, Urine, CSF
Core unit analytics
  • Rack: 5 position rack, RD standard rack
  • Rack types: Routine, STAT, Control, Calibrator, Rerun (manual), Wash
  • Tray: Tray with 15 racks/75 samples, RD standard tray
  • STAT port: STAT samples are processed with true STAT interrupt
Sample container types
  • Primary tubes: 5 to 10 mL; 16 x 100, 16 x 75, 13 x 100, 13 x 75 mm
  • Sample cup: 2.5 mL
  • Micro cup: 1.5 mL, (exception: cobas e 601 module)
  • Cups on tube: Cup on top of a 16 x 75/100 mm tube; Cup on top of one non standard tube
  • False bottom tube (FBT): One type is definable
Sample volume 1–35 µL
Sample dilution 3–121 times
Sample clot detection Available for cobas c 501 and cobas e 601 module
Minimum sample volume
  • Primary tubes: 700 µL
  • Sample cup: 100 µL
  • Micro cup (FTB): 50 µL
Sample barcode types Code 128; Codabar (NW 7); Interleaved 2 of 5; Code 39
System interfaces RS 232 serial interface, bi-directional Interface to cobas link data station for cobas teleservice functionalities and automatic download
Sample data base 10.000 routine/STAT samples
Test methods For photometric modules: 1 point, 1 point + prozone check, 2 point, 2 point kinetic, 2 point + prozone check, 3 point, 1 point + kinetics Rate A, Rate A + serum index, Rate A with blank, Rate B
Calibrator/QC input Via specified racks through the input buffer or STAT port
Calibration methods Start-up, Re-calibration For photometric modules: Linear, non-linear multi-points, 2 point calibration, K-factor up to 100 different calibrators pre-programmable Storage of up to 180 curves Preventive calibration of the stand-by cobas c and cobas e packs on cobas c 501: Two k-factor can be defined for different sample types
QC methods For e- and photometric modules: Real-time QC, individual QC, cumulative QC Up to 100 controls pre-programmable Preventive QC after calibration of the stand-by cassettes/rack packs Auto QC: QC without operator intervention (timer triggered)
Rerun/reflex function Automatic rerun and manual rerun; Automatic reflex is supported by the system, reflex request to be provided by Roche Middleware Solutions
Electrical requirements
  • Power requirements: 230 Volts AC; 110 Volts AC 2.4 kVA (for cobas c 501 | e 601)
  • Frequency: 50 Hz or 60 Hz +/- 0.5%
Water/waste requirements
  • Water: Bacteria free, deionised water supply: resistance of < 1,0 µS/cm
  • Water pressure: 0.5 – 3.5 kg/cm3, (49–343 Kpa)
  • Biohazards waste: Separate container behind the system
  • L. concentrated: Central drain port, diameter: = 50 mm / 2 inches
  • Waste drain < waste: 100 mm above the floor / 4 inches
Water consumption
  • Max flow rate: cobas c 501 module: approx. 40 L/hour
  • Typical consumption: cobas e 601 module: approx. 30 L/hour
Operational conditions
  • Ambient temperature: 15 to 32°C / 59 to 90°F
  • Ambient humidity: 30 to 85% (RH, without condensation)
  • Heat output: 1.5 kW (5400 kJ/hr for cobas c 501, 4320 kJ/hr for cobas e 601)
  • Noise output: < 65 dB
Physical dimensions
  • Width: 188 to 498 cm / 74 to 196 inches
  • Core unit: 69 cm / 27.2 inches cobas c or cobas e module: 120 cm / 47.2 inches
  • Depth: cobas c or cobas e module: 98 cm / 38.6 inches Core unit: 104 cm / 41 inches
  • Height: 130 cm / 51 inches
  • Control unit: Width: 80 cm / 31.5 inches, depth: 80 cm / 31.5 inches
  • cobas c 501 module: 330 kg / 730 lbs
  • cobas e 601 module: 360 kg / 795 lbs
  • Core unit (sample loader, control unit, rack rotor): 180 kg / 400 lbs

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Strategic Resource Center Decision Guide

cobas c 501


Iron Binding Capacity - Unsaturated
Iron Gen.2
Tina-quant Ferritin Gen.4
Tina-quant Soluble Transferrin Receptor
Tina-quant Transferrin ver.2

Cardiac/Cardiac Markers

Cardiac C-Reactive Protein (Latex) High Sensitive
Cholesterol Gen.2
HDL-Cholesterol Gen.4
LDL-Cholesterol Gen.3
Tina-quant Apolipoprotein A-1 ver.2
Tina-quant Apolipoprotein B ver.2
Tina-quant D-Dimer
Tina-quant Lipoprotein (a) Gen.2
Tina-quant Myoglobin Gen.2


Tina-quant D-Dimer


Amphetamines II
Barbiturates Plus
Benzodiazepines Plus
Cannabinoids II
Cocaine II
Ethanol Gen.2
Lysergic Acid Diethylamide
Methadone II
Opiates II
Phencyclidine Plus
Propoxyphene Plus


Glucose HK
Tina-quant Albumin Gen.2
Tina-quant Hemoglobin A1c Gen.2
Tina-quant Hemoglobin A1c Gen.3 - Hemolysate and Whole Blood Application

General Chemistry

Alanine Aminotransferase acc. to IFCC with pyridoxal phosphate activation
Alanine Aminotransferase acc. to IFCC without pyridoxal phosphate activation
Albumin BCP
Albumin Gen.2
Alkaline Phosphatase
Aspartate Aminotransferase acc. to IFCC with pyridoxal phosphate activation
Aspartate Aminotransferase acc. to IFCC without pyridoxal phosphate activation
Bicarbonate Liquid
Bilirubin Total Gen.3
Bilirubin direct
Calcium Gen.2
Cholinesterase Gen.2
Creatine Kinase
Creatinine Jaffé Gen.2
Creatinine plus ver.2
Direct Bilirubin
Lactate Dehydrogenase acc. to IFCC ver.2
Lactate Gen.2
Lipase colorimetric assay
Magnesium Gen.2
Phosphate (Inorganic) ver.2
Total Protein Gen. 2
Total Protein Urine/CSF Gen.3
Uric Acid ver.2
a-Amylase EPS ver.2
α-Amylase EPS Pancreatic
γ-Glutamyltransferase ver.2 Standardized against IFCC / Szasz




Tina-quant Myoglobin Gen.2

Specific Proteins

C-Reactive Protein
C-Reactive Protein Gen.3
Cardiac C-Reactive Protein (Latex) High Sensitive
Homocysteine Enzymatic Assay
Immunoglobulin A
Rheumatoid Factors II
Tina-quant Antistreptolysin O
Tina-quant Complement C3c ver.2
Tina-quant Complement C4 ver.2
Tina-quant Cystatin C Gen.2
Tina-quant Haptoglobin ver.2
Tina-quant IgG Gen.2
Tina-quant IgM Gen.2
Tina-quant α1-Acid Glycoprotein Gen.2
Tina-quant α1-Antitrypsin ver.2
Tina-quant β2-Microglobulin

Specimen Validity

ONLINE DAT Specimen Validity Test Chromate
ONLINE DAT Specimen Validity Test Creatinine
ONLINE DAT Specimen Validity Test Nitrite
ONLINE DAT Specimen Validity Test Oxidant
ONLINE DAT Specimen Validity Test Specific Gravity
ONLINE DAT Specimen Validity Test pH


Mycophenolic Acid
ONLINE TDM Acetaminophen Gen.2
ONLINE TDM Carbamazepine Gen.4
Valproic Acid

cobas e 601


Elecsys Ferritin
Elecsys Folate RBC
Elecsys Folate RBC
Folate III
Folate RBC
Vitamin B12 II

Bone Markers

25-Hydroxyvitamin D
Elecsys PTH
Elecsys PTH STAT
Elecsys Vitamin D total II
Osteocalcin (OCN)
β-CrossLaps/serum (β-CTx in serum)

Cardiac/Cardiac Markers

CK-MB - the MB isoenzyme of creatine kinase
CK-MB - the MB isoenzyme of creatine kinase (STAT "Short Turn Around Time")
Elecsys Troponin T Gen 5 STAT
Myoglobin STAT (Short Turn Around Time)
Troponin I
Troponin I STAT (Short Turn Around Time)
Troponin T
Troponin T STAT (Short Turn Around Time), CARDIAC T


Elecsys Insulin


Elecsys ACTH
Elecsys Estradiol III
Elecsys HCG + β
Elecsys Prolactin II
Elecsys SHBG

General Chemistry

CK-MB - the MB isoenzyme of creatine kinase
CK-MB - the MB isoenzyme of creatine kinase (STAT "Short Turn Around Time")

Growth Hormones

Elecsys IGF-1
Human growth hormone


Anti-HAV IgM
Antibody to hepatitis B surface antigen (anti-HBs)
Elecsys Anti-HBc II
Elecsys Anti-HBc IgM
Elecsys Anti-HCV II
Elecsys Anti-HCV II
Elecsys HBsAg II
Elecsys HBsAg II
Elecsys HBsAg II
Elecsys HBsAg II
HBsAg Confirmatory Test
HBsAg Confirmatory Test
Hepatitis B surface antigen
Hepatitis B surface antigen
Total antibodies (IgM and IgG) to the hepatitis A virus

Infectious Disease

Cytomegalovirus IgM
Elecsys CMV IgM
Elecsys HSV-1 IgG
IgG antibodies to Rubella virus
IgM antibodies to Rubella virus
Toxo IgG
Toxo IgM

Rheumatoid Arthritis

Cyclic Citrullinated Peptide Antibody


CK-MB - the MB isoenzyme of creatine kinase
CK-MB - the MB isoenzyme of creatine kinase (STAT "Short Turn Around Time")
Elecsys PTH
Elecsys PTH STAT
Elecsys Troponin T Gen 5 STAT
Human chorionic gonadotropin (Short Turn Around Time)
Myoglobin STAT (Short Turn Around Time)
Troponin I
Troponin I STAT (Short Turn Around Time)
Troponin T
Troponin T STAT (Short Turn Around Time), CARDIAC T



Specific Proteins

Immunoglobulin E



Thyroid Function

Antibodies to thyroid peroxidase
Elecsys Anti-TSHR
Elecsys Anti-Tg
Elecsys FT4 II
Elecsys T3
Free Triiodothyronine
hCT - human calcitonin

Tumor Markers

AFP α1-fetoprotein
AFP α1-fetoprotein
Cancer Antigen 125
Cancer Antigen 15-3 II
Carbohydrate Antigen 19-9
Carcinoembryonic antigen
Carcinoembryonic antigen
Elecsys free PSA
Elecsys total PSA
Elecsys total PSA
Human epididymal protein 4
Prostatic Specific Antigen

Women's Health

Elecsys AMH

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